You’re right to be concerned. Wellbutrin and Adderall both act on neurotransmitters, and combining them can increase the risk of overstimulation, anxiety, or cardiovascular issues. Some people are fine with the combination, but others experience serious side effects. If your friend is starting both, they should be closely monitored by their doctor. It’s important to stay aware of how their body reacts to the meds, especially in the first few weeks.